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Somatoline multidose bottle with dispenser is indicated for the treatment of cellulite and localized adipose states.
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Therapeutic indications

States of localized adiposity accompanied by cellulite.SOMATOLINE is indicated in adults.

Dosage and method of use

Posology and method of administration Sachets : apply locally 20 g of product per day (equal to 2 sachets) for the first two consecutive days, then 10 g of product (equal to 1 sachet) per day or every other day. If the product is to be used on the thighs, apply 1 sachet (10 g) to each thigh for the first two days. The following days half a sachet (5 g) per thigh. Multidose bottle with dispenser : (4 pumps correspond to 10 g of product). Apply locally 20 g of product per day (equal to 8 sprays) for the first two days, then 10 g of product (equal to 4 sprays) per day or every other day. If the product is to be used on the thighs, apply a dose corresponding to 4 sprays (10 g) for each thigh for the first two days. The following days, 2 pumps (5 g) per thigh. To obtain 1 delivery, press the dispenser all the way down. Each treatment cycle can go from a minimum of 15 - 20 days to a maximum of 2 - 3 months and can be repeated at various time intervals. Massage the product in the area to be treated (the surface of which should not, as a rule, exceed 15 cm per side), until completely absorbed. Followed by a second deeper massage, lasting a few minutes (5'– 10 '). If the skin is oily or thickened, it is advisable to first wash the area to be treated, dry well and then practice a simple massage until a slight reddening is produced; then proceed with the application of the treatment as described above; the clinical results generally begin to become evident towards the end of the second week of treatment. Pediatric population Safety and efficacy in children and adolescents have not yet been demonstrated. No data are available.


Hypersensitivity to the active substances or to any of the excipients listed in section 6.1. Iodine intolerance. Generally contraindicated in pregnancy and lactation (see section 4.6).

Side effects

Cases with symptoms attributable to impaired thyroid function have been reported very rarely. Reporting of suspected adverse reactions Reporting of suspected adverse reactions that occur after authorization of the medicine is important, as it allows continuous monitoring of the benefit / risk ratio of the medicine. Healthcare professionals are asked to report any suspected adverse reactions via the website: http://agenziafarmaco.gov.it/it/responsabili

Special warnings

The use, especially if repeated or prolonged, of products for topical use can give rise to sensitization phenomena. If this occurs, discontinue treatment and assess the need for appropriate therapy. Do not use near the mucous membranes. SOMATOLINE contains para-hydroxybenzoates which can cause allergic reactions (even delayed).

Pregnancy and breastfeeding

There are no experimental or clinical data to argue against the use of the product during pregnancy. However, prudence advises against applying the product during pregnancy or breastfeeding.

Expiration and retention

This medicine does not require any special storage conditions.

Interactions with other drugs

There are no phenomena of intolerance or incompatibility with other drugs.


There was no evidence of overdose.

Active principles

100 g of emulsion contain: active ingredients: levothyroxine 100 mg escin 300 mg Excipients with known effects: methyl p-hydroxybenzoate, propyl p-hydroxybenzoate. For the full list of excipients, see section 6.1.


Glyceryl monostearate AE, xanthan gum, liquid paraffin, decyloleate, sorbitol 70% not crystallizable, polyacrylamide isoparaffin laureth-7, imidazolidinylurea, methyl para – hydroxybenzoate, propyl para – hydroxybenzoate, citric acid monohydrate, rose perfume, purified water.

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