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Indicated in case of Vitamin C deficiency.

Beneficial action on the immune system.

Deductible over-the-counter drug.

Antioxidant action.

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Therapeutic indications

Deficiency states from ascorbic acid (pregnancy, lactation, increased vitamin requirement).

Dosage and method of use

Dosage Administer 1 to 3 tablets per day in a glass of water. Method of administration For oral use. Dissolve an effervescent tablet in a glass of water and immediately drink the solution obtained.


Hypersensitivity to the active substance, to other closely related substances from a chemical point of view or to any of the excipients listed in section 6.1. Oral administration of ascorbic acid is contraindicated in case of diarrhea or other gastrointestinal disturbances.

Side effects

Ascorbic acid is generally well tolerated. High doses can cause diarrhea and the formation of calcium oxalate kidney stones. Nausea and stomach cramps may occur. Hypersensitivity reactions may occur in predisposed subjects. At higher than recommended dosages, headaches and gastrointestinal upset have been reported. Reporting of suspected adverse reactions Reporting of suspected adverse reactions that occur after authorization of the medicine is important, as it allows continuous monitoring of the benefit / risk ratio of the medicine. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system at www.aifa.gov.it/content/segnalazioni-reazioni-avverse.

Special warnings

Ascorbic acid should be administered with caution in patients with hyperoxaluria. Vitamin C should be used with caution by people who suffer, or have suffered in the past, from nephrolithiasis (kidney stones) and by those with G6PD (glucose-6-phosphate dehydrogenase) deficiency, hemochromatosis, thalassemia or sideroblastic anemia. Ascorbic acid can alter, at high doses, the results of the most common diagnostic tests, in particular for glycosuria, by non-specific means, giving false positive results. It is therefore advisable to stop taking the product a few days before proceeding with the glucose dosage in the urine. Do not use for prolonged treatments. This medicine contains: • sucrose; Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption, or sucrase isomaltase insufficiency should not take this medicine. • about 12.5 mmol (or 287 mg) of sodium per effervescent tablet. To be taken into consideration in people with reduced kidney function or who follow a low sodium diet. • aspartame: a source of phenylalanine. It can be harmful to patients with phenylketonuria. • E 110 dye (sunset yellow) and E 102 dye (tartrazine): can cause allergic reactions.

Pregnancy and breastfeeding

Administration during pregnancy and lactation is among the therapeutic indications. Unless otherwise prescribed by a doctor, it is recommended not to exceed the dose of 1 g / day.

Expiration and retention

Keep the container tightly closed in order to protect from moisture. In fact, the effervescent tablets are sensitive to humidity and in the cap of the container there is a desiccant that serves to protect the tablets from any humidity that could penetrate them. Store below 25 ° C.

Interactions with other drugs

Ascorbic acid can increase the apparent half-life of paracetamol. Concomitant administration of aluminum-containing antacids may increase the elimination of aluminum in the urine. Concomitant administration of antacids and ascorbic acid is not recommended, especially in patients with renal insufficiency. Concomitant administration of ascorbic acid and deferoxamine increases urinary iron excretion. Cases of cardiomyopathy and congestive heart failure have been reported in patients with idiopathic hemochromatosis and thalassemia treated with deferoxamine and subsequently treated with ascorbic acid. In these patients, ascorbic acid should be used with caution and their cardiac function should be monitored.


If ascorbic acid is administered in excess of the body's requirements, the unused portion is eliminated in the urine: therefore there is no danger of overdose. Nevertheless, occasionally very high quantities of ascorbic acid can cause slight gastrointestinal disturbances consisting mainly of laxative phenomena. In such cases, treatment should be discontinued. Ascorbic acid can cause acidosis or hemolytic anemia in some individuals with glucose-6-phosphate dehydrogenase deficiency. In case of massive overdose of ascorbic acid, renal failure may occur.

Active principles

Each effervescent tablet contains: Active principle: ascorbic acid 1000 mg. Excipients with known effects: sucrose, sodium, aspartame, color E 110 (sunset yellow) and color E 102 (tartrazine). For the full list of excipients, see section 6.1.


Each tablet contains: Excipients: sodium bicarbonate, sucrose, tartaric acid, citric acid, leucine, citronjus aroma, sodium chloride, sodium saccharin, aspartame, coloring E 110 (sunset yellow), coloring E 102 (tartrazine).

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