ZEROFLOG * COLLUT 1FL 200ML
Symptomatic treatment of irritative-inflammatory states also associated with pain in the oropharyngeal cavity (eg gingivitis, stomatitis, pharyngitis), also as a consequence of conservative or extractive dental therapy.
Dosage and method of use
Mouthwash The recommended dose is 2-3 rinses or gargles per day with 15 ml (1 scoop or 1 sachet) of pure or diluted mouthwash in a little water. Oral mucosal spray The recommended dose is 2 sprays three times a day addressed directly to the affected area. Each spray delivers 0.2 ml of solution equivalent to 0.3 mg of active ingredient.
Hypersensitivity to product components or substances closely related from a chemical point of view to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs
Diclofenac is generally well tolerated and side effects rarely occur. Gastrointestinal disorders
| Burning sensation in the mouth || Frequency not known |
Clinical studies conducted with ZEROFLOG Collutorio have shown, especially for prolonged treatments, the onset of the following side effects: Gastrointestinal disorders
Irritative phenomena affecting the oral mucosa, generally mild. Respiratory pathologies
Cough. In clinical studies with ZEROFLOG oral mucosal spray solution, the following undesirable effects were observed only in a small number of patients treated: a) mild severity Gastrointestinal disorders
nausea, dyspepsia Vascular pathologies
Hypotension Musculoskeletal and connective tissue disorders
chills Pathologies of vision
b) moderate changes in vision Central nervous system disorders
headache Skin and subcutaneous tissue disorders
changes in the mucous membranes.
Any involuntary swallowing of the dose of mouthwash used for rinsing and gargling does not cause any harm to the patient as it is equivalent to one fifth / sixth of the dose prescribed by the systemic dosage. The use, especially if prolonged, of topical preparations can give rise to sensitization phenomena, in which case it is necessary to interrupt the treatment and institute, if necessary, suitable therapy. Although systemic absorption is limited, Zeroflog should be administered with caution to patients with a history of gastrointestinal bleeding or perforation related to previous active treatments or a history of recurrent peptic haemorrhage / ulcer (two or more distinct episodes of proven ulceration or bleeding).
Pregnancy and breastfeeding
In pregnant and lactating women, the product should be used in cases of real need, under direct medical supervision.
Expiration and retention
- Mouthwash (bottle and sachets) Store below 25 ° C -Spray solution for oral mucosa Store below 25 ° C
Interactions with other drugs
As systemic absorption is limited under normal conditions of use, interactions with other medicinal products are unlikely.
There have been no reports of overdosing with ZEROFLOG
ZEROFLOG Mouthwash 100 ml of mouthwash contain: active ingredient: Diclofenac acid (2 - [(2,6-dichlorophenyl) amino] benzenacetic acid) g 0.074 Excipients: sodium benzoate A 15 ml sachet contains: active ingredient: Diclofenac acid (2- [acid (2,6-dichlorophenyl) amino] benzenacetic) g 0.011 excipients: sodium benzoate For the full list of excipients see section 6.1 ZEROFLOG 0.022g / 15ml spray solution for oral mucosa 15 ml of solution contain: active ingredient: Diclofenac acid (2 - [(2,6-dichlorophenyl) amino] benzenacetic acid) g 0.022 excipients: sodium benzoate For the full list of excipients see section 6.1
ZEROFLOG Mouthwash (bottle and sachets) Non crystallizable liquid sorbitol, choline (base), sodium benzoate, disodium edetate, acesulfame potassium, mint natural flavoring, natural peach flavoring, Ponceau red dye (E124) purified water. ZEROFLOG spray solution for oral mucosa Non crystallizable liquid sorbitol, choline chloride, disodium edetate, sodium benzoate, acesulfame potassium, essential oil of mint, peach natural flavoring, Ponceau red dye (E 124), Ethanol 96%, sodium hydroxide, purified water.