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Connettivina plus gauzes provides an antibacterial, regenerating and healing action.

Indicated in case of wounds, sores and skin ulcers.

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Final Price €14.20
Regular Price €15.40
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Therapeutic indications

Local treatment of mild sores Local treatment of I and II degree burns

Dosage and method of use

CONNETTIVINA PLUS 2 mg / g + 10 mg / g cream: spread an even layer of cream 2–3 mm thick over the entire site of the lesion, once or twice a day. CONNETTIVINA PLUS 2 mg + 40 mg impregnated gauzeCONNETTIVINA PLUS 4 mg + 80 mg impregnated gauze CONNETTIVINA PLUS 12 mg + 240 mg impregnated gauze: Apply one or more medicated gauze two or more times a day depending on the extent of the lesions. Before applying CONNETTIVINA PLUS, the affected areas must be cleaned preferably with sterile physiological solution (NaCl 0.9%) and disinfected with antiseptics preferably containing povidone iodine or chlorhexidine. If necessary, surgical cleaning should be performed. In the treatment of burns, it is preferable to clean the lesions with water or sterile physiological solution alone, avoiding disinfection with antiseptic agents before applying Connettivina PLUS cream or impregnated gauze. After cleansing the injured parts, spread an even layer of cream 2 or 3 mm thick or apply the impregnated gauze. Application should continue as long as there is a possibility of infection and until complete healing.


Hypersensitivity to the active substances and other closely related substances from a chemical point of view or to any of the excipients listed in section 6.1.

Side effects

After the application of CONNETTIVINA PLUS, local reactions (pain, burning, itching) may also occur of an allergic nature. Since systemic administration of sulfonamides can cause adverse reactions such as renal failure, toxic hepatitis, agranulocytosis, thrombocytopenia and leukopenia, it cannot be excluded that local treatment of large parts of the body with CONNETTIVINA PLUS may give rise to undesirable effects typical of sulfonamides administered for systemicallyReporting of suspected adverse reactionsReporting of suspected adverse reactions that occur after authorization of the medicine is important, as it allows continuous monitoring of the benefit / risk ratio of the medicine. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system at www.agenziafarmaco.gov.it/it/responsabili.

Special warnings

CONNETTIVINA PLUS should be used with caution in subjects who have shown previous allergies to sulfonamides and in the presence of hepatic or renal insufficiency.

Pregnancy and breastfeeding

In the absence of data on the effects of the medicinal product on the fetus, CONNETTIVINA PLUS should not be used during pregnancy and lactation unless the doctor considers that the therapeutic benefits outweigh the possible risks.

Expiry and retention

Store at a temperature below 30 ° C.

Interactions with other drugs

Local proteolytic enzymes, applied simultaneously with CONNETTIVINA PLUS, can be inactivated by the presence of silver ions. Do not use simultaneously with disinfectants containing quaternary ammonium salts as hyaluronic acid can precipitate in their presence.


There are no known cases of overdose.

Active principles

CONNECTIVINE PLUS 2 mg / g + 10 mg / g cream1 g of cream contains 2 mg of hyaluronic acid sodium salt and 10 mg of silver sulfadiazine.CONNETTIVINA PLUS 2 mg + 40 mg impregnated gauzeEach 10x10 cm gauze is impregnated with 4 g of cream containing 2 mg of hyaluronic acid sodium salt and 40 mg of silver sulfadiazine.CONNETTIVINA PLUS 4 mg + 80 mg impregnated gauzeEach 10x20 cm gauze is impregnated with 8 g of cream containing 4 mg of hyaluronic acid sodium salt and 80 mg of silver sulfadiazine.CONNETTIVINA PLUS 12 mg + 240 mg impregnated gauzeEach 20x30 cm gauze is impregnated with 24 g of cream containing 12 mg of hyaluronic acid sodium salt and 240 mg of silver sulfadiazine. For the full list of excipients, see section 6.1.


CONNETTIVINA PLUS 2 mg / g + 10 mg / g cream Polyethylene glycol 400 monostearate - decyl ester of oleic acid - emulsifying wax - glycerol - sorbitol solution 70% - purified waterCONNETTIVINA PLUS 2 mg + 40 mg impregnated gauze CONNETTIVINA PLUS 4 mg + 80 mg impregnated gauze CONNETTIVINA PLUS 12 mg + 240 mg impregnated gauzePolyethylene glycol 4000 - glycerol - purified water

22 Items

Data sheet

u.est. 10 impregnated gauzes (10x10 cm)
Product Type
ATC code
ATC description
Other cicatrisants
Therapeutic Group
Sulfonamide antibacterials
Active principle
silver sulfadiazine + hyaluronic acid
Pharmaceutical form
Type of Administration
gauze / handkerchief
10 gauzes
4 grams
Quantity of the Active Ingredient
2MG (hyaluronic acid) + 40MG (silver sulfadiazine)
Recipe required
SOP - non-prescription medicine