• EG SpA
  • 010386011
Hirudoid is a drug based on the active ingredient glycosaminoglycan polysulfate - belonging to the category of Heparin and specifically Heparin or heparinoid for topical use. Hirudoid can be prescribed with SOP Recipe - non-prescription medicine. Superficial thrombophlebitis and phlebitis - states of inflammation of the varices - hematomas.
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Therapeutic indications

Superficial thrombophlebitis and phlebitis, variceal inflammation states, hematomas.

Dosage and method of use

Cream: in small inflammatory processes, apply a 3-5 cm long stream of cream 1-2 times a day (about 0.5-1 g) or cover with a gauze tablet coated with Hirudoid 25000 IU cream. The cream can be lightly rubbed in the vicinity of the diseased area; never rub on the inflamed part. In more extensive processes, larger quantities of the drug are required: about 25 cm (about 4 to 6 g) of cream per day. Practice the treatment for 3-4 days, after this period halve the dose until the symptoms disappear; Gel: apply a 5-10 cm length of gel several times a day. In case of inflamed surfaces it is advisable not to rub on the diseased part but in the immediate vicinity. Hirudoid 25000 IU gel is particularly suitable for percutaneous therapy of large surfaces. Larger quantities of the drug are then required. Practice the treatment for 3-4 days; after this period, halve the dose until the symptoms disappear.


Hypersensitivity to the active substance, to a heparinoid or to any of the excipients listed in section 6.1.

Side effects

No undesirable effects known Reporting of suspected adverse reactions The reporting of suspected adverse reactions occurring after authorization of the medicinal product is important, as it allows continuous monitoring of the benefit / risk ratio of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system at

Special warnings

The use, especially if prolonged, of products for cutaneous use can give rise to sensitization phenomena, in which case the treatment must be interrupted. Hirudoid 25000 IU gel and cream contain an alcohol among the excipients and therefore should not be applied to open wounds or mucous membranes. Important information about some of the ingredients Hirudoid 25000 IU cream contains parahydroxybenzoates which can cause allergic reactions (possibly delayed). contains lanolin and cetylstearyl alcohol which can cause local skin reactions (eg contact dermatitis). Hirudoid 25000 IU gel This medicinal product contains 5 mg of propylene glycol per g of gel.

Pregnancy and breastfeeding

There are no special precautions or warnings for the product in case of pregnancy and lactation

Expiration and retention

This medicine does not require any special storage conditions.

Interactions with other drugs

There are no known interactions with other medicines


No particular effects due to overdose are reported.

Active principles

100 g of cream contain: Active ingredient: glycosaminoglycanopolysulphate (PM 5700-13700) 0.3 g equal to 25000 IU Excipients with known effect: 7.515 g of lanolin, 0.160 g of methyl parahydroxybenzoate, 0.040 g of propyl parahydroxybenzoate and 3.105 g of cetostearyl alcohol. 100 g of gel contain: Active ingredient: glycosaminoglycanopolysulphate (PM 5700-13700) 0.3 g, equal to 25000 IU Excipients with known effect: 0.50 g of propylene glycol (E1520). For the full list of excipients, see section 6.1.


Cream: glycerin, potassium hydroxide, stearic acid, lanolin, cetostearyl alcohol, myristic alcohol, thymol, methyl parahydroxybenzoate, propyl parahydroxybenzoate, isopropyl alcohol, purified water. Gel: isopropanol, polyacrylic acid, propylene glycol (E1520), sodium hydroxide, purified water.

24 Items

Data sheet

25,000 IU cream tube 40 g
Product Type
ATC code
ATC description
Organic heparinoids
Therapeutic Group
Active principle
glycosaminoglycan polysulfate
Pharmaceutical form
Type of Administration
1 tube
40 grams
Quantity of the Active Ingredient
Recipe required
SOP - non-prescription medicine